美國cir化妝品原料安全使用指南

1、Quick Reference TableReview Conclusion****Explanation Journal Citation ?Ingredient Name or Group Name S SQ I Z U UNS Use concentration for S conclusionConcentration or other limitation on use for SQ conclusionSafety conc

2、ern for U or UNS conclusion1,2-butanediol 1 not in use at the time* IJT 31(S2): 147-168, 20121,2-hexanediol 1 0.00005 to 10% IJT 31 (S2): 147-168, 20121,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer 1 Final report

3、 06/2016 available from CIR1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate 1 safe as an oxidative hair dye Final report 03/2016 available from CIR1-Naphthol 1 up to 3% in hair coloring productsJACT 8(4):749-68, 1989 confirme

4、d 12/062,4-Diaminophenoxyethanol HCl 1 up to 2% Final Amended Report 12/07 Available from CIR JACT 10(1):113-34, 1991 (original report)2,4-Diaminophenoxyethanol Sulfate (amended) 1 up to 2% Final Amended Report 12/07 Ava

5、ilable from CIR JACT 10(1):113-34, 1991 (original report)2-Amino-3-Hydroxypyridine 1 Final report 09/2014 available from CIR2-Amino-3-Nitrophenol 1 up to 2% in hair dyes IJT 28(S3): 217-251, 20092-Amino-4-Nitrophenol 1 c

6、oncentration not reported * IJT 28(S3): 217-251, 20092-Amino-4-Nitrophenol Sulfate 1 not in current use * IJT 28(S3): 217-251, 20092-Amino-5-Nitrophenol 1 not in current use * IJT 28(S3): 217-251, 20092-Chloro-p-Phenylen

7、ediamine 1 up to 0.1% JACT 11(4):521-530, 19922-Chloro-p-Phenylenediamine Sulfate 1 up to 1.0% JACT 11(4):521-530, 19922-Methyl-5-Hydroxyethylaminophenol 1 up to 5% JACT 9(2):185-202, 1990 confirmed 08/062-Methyl Resorci

8、nol 1 up to 2% JACT 5(3):167- 203, 1986 confirmed 12/062-Nitro-p-Phenylenediamine 1 up to 1% JACT 4 (3):161-202, 1985 confirmed 11/03 IJT 25(S2), 20062-oleamido-1,3-octadecanediol 1 safe as used Final report 03/2015 avai

9、lable from CIRQuick Reference TableReview Conclusion****Explanation Journal Citation ?Ingredient Name or Group Name S SQ I Z U UNS Use concentration for S conclusionConcentration or other limitation on use for SQ conclus

10、ionSafety concern for U or UNS conclusionAcetyl Triethyl Citrate 1 up to 7% IJT 21 (S2):1-17, 2002Acetyl Trihexyl Citrate 1 not in current use * IJT 21(S2):1-17, 2002Acetyl Trioctyl Citrate 1 not in current use * IJT 21(

11、S2):1-17, 2002Acrylates/bis-hydroxypropyl dimethicone crosspolymer 1 not in current use* IJT 33 (S2): 65-115, 2014Acrylates/dimethiconol acrylate copolymer 1 up to 0.5% Final report 12/10 available from CIRAcrylates/Ethy

12、lhexyl Acrylate/Styrene Copolymer 1 not in current use* Final report 09/2014 available from CIRAcrylates C10/30 Alkyl Acrylate Crosspolymer 1 1 when used as described in assessment, 0.0002-5%data does not support use whe

13、n polymerized in benzeneFinal report 11/2011 available from CIRActinidia Chinensis (Kiwi) Seed Oil 1 up to 0.1% Final report 03/11 available from CIRAdansonia Digitata Oil 1 up to 0.01% Final report 03/11 available from

14、CIRAdansonia Digitata Seed Oil 1 not in current use* Final report 03/11 available from CIRAdipic Acid 1 0.000001% in leave- on; 18% in rinse- offIJT 31 (S1):5-76, 2012Adipic acid/1,4 butanediol/terephthalate copolymer 1

15、not in current use* IJT 33(S3):36-47, 2014Agar 1 Final report 09/2015 available from CIRAgarose 1 Final report 09/2015 available from CIRAlanine 1 3.0 x 10-7 to 0.1% IJT 32(S4):41-64, 2013Alcaligenes polysaccharides 1 0.

16、005 to 0.3% Final report 09/12 available from CIRAlcohol Denat. denatured with t-Butyl Alcohol, Denatonium Benzoate, Diethyl Phthalate, or Methyl Alcohol1 up to 99% IJT 27 (S1):1-43, 2008Aleurites Moluccanus Bakoly Seed

17、Oil 1 not in current use* Final report 03/11 available from CIRAleurites Moluccanus Seed Oil 1 0.00001 to 5% Final report 03/11 available from CIRAlgae Exopolysaccharides 1 Final report 09/2015 available from CIRAlgin 1

18、Final report 09/2015 available from CIRAlginic Acid 1 Final report 09/2015 available from CIRAlkyl aryl sulfonate hydrotropes 1 safe for use in cosmetics when formulated to be non-irritatingIJT 30(Suppl. 3):270-283, 2011